DAILY UPDATE: Medicaid, HIV Vaccine, CDC and the Rising Stock Markets

MEDICAL EXECUTIVE-POST TODAY’S NEWSLETTER BRIEFING

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CITE: https://www.r2library.com/Resource

Stat: 2%. That’s the portion of Medicaid expansion enrollees who were either not working or in school due to “lack of interest” in finding a job. (Robert Wood Johnson Foundation)

Quote: “It’s just devastating. So much human toil has gone into this. Just when it looked like we could beat this virus, we’re going to give up.”—Dennis Burton, a Scripps Research Institute immunologist, on how a new HIV vaccine was about to start clinical trials before federal funding cuts (NPR)

Read: A look at HHS Secretary RFK Jr.’s new appointees to the CDC vaccine advisory panel. (Stat)

CITE: https://tinyurl.com/2h47urt5

🟢 What’s up

  • The wait is finally over: US Steel climbed 5.10% after President Trump signed an executive order approving its takeover by Nippon Steel.
  • Roku jumped 10.43% after announcing a partnership with Amazon that gives advertisers the ability to reach roughly 80% of American households with connected TVs.
  • Advanced Micro Devices rose 8.81% on an upgrade from Piper Sandler analysts, who think the semi stock’s AI business will boom.
  • EchoStar exploded 49.11% after Trump pushed the FCC to resolve its ongoing spectrum dispute with the satellite company.
  • Victoria’s Secret rose 2.36% on reports that the struggling retailer has attracted the attention of an activist investor.
  • Sage Therapeutics soared 35.37% on the news that it will be acquired by Supernus Pharmaceuticals in a $795 million deal.
  • MGM Resorts climbed 8.10% after the casino company revealed that its Bet MGM online gambling platform is expected to pull in more revenue than previously thought.
  • Kering, the parent company of Gucci, Yves Saint Laurent, and other luxury brands, popped 12.37% on the news that it has convinced Renault’s CEO to run the company.

What’s down

  • Sarepta Therapeutics plunged 42.12% after the pharma company reported a second death of a patient taking its Duchenne muscular dystrophy treatment Elevidys.
  • Reports that Iran wants to end hostilities pushed oil prices lower this afternoon, hurting shares of energy stocks like APA Corp (down 2.43%), Devon Energy (down 1.45%) and ConocoPhillips (down 2.02%).

CITE: https://tinyurl.com/tj8smmes

Visualize: How private equity tangled banks in a web of debt, from the Financial Times.

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DAILY UPDATE: “Medical Properties Trust” Tanks, FDA Approves Canadian Drugs and Medicare Advantage Health Plan [Part C] Patient Traps

By Staff Reporters

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Markets: Stocks climbed a bit on Friday as investors took in the news that the US added more jobs than expected in December, capping off an epic 2023 for the labor market. But it wasn’t a bright start to the year, as all three major averages broke a nine-week winning streak. Stock spotlight: The country’s largest hospital landlord, Medical Properties Trust, tanked after revealing that its biggest tenant was $50 million behind on rent.

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Yesterday, the Food and Drug Administration (FDA) approved Florida’s request to import bargain medications from the country. It’s the first state to get permission from the agency to bring in medications from Canada under a law Congress passed 20 years ago to help Americans pay less for drugs. Florida officials say ordering cheaper drugs for conditions like HIV and diabetes from Canadian wholesalers will save Medicaid and other state programs $150 million over the first year.

CITE: https://www.r2library.com/Resource

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Older Americans say they feel trapped in Medicare Advantage plans.

READ HERE: http://tinyurl.com/yck2yb8z

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PEPFAR’s Uncertain Future for AIDS Relief

By Staff Reporters

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An impactful government program is facing an uncertain future. PEPFAR—an acronym for the President’s Emergency Plan for AIDS Relief—was created by former President George W. Bush in 2003 and is credited with saving 25 million lives around the world. Through the program, the US government has invested more than $100 billion in treatment for HIV-AIDS and related illnesses by providing training, medical infrastructure, and antiretroviral drugs. PEPFAR remains the largest commitment by a country to confront a single disease, according to KFF.

Since its inception, PEPFAR has been renewed every five years with bipartisan support. But that wasn’t the case in 2023, as lawmakers let the program expire at the end of September.

CITE: https://www.r2library.com/Resource

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2023 NOBEL PRIZE: MEDICINE Katalin Karikó and Drew Weissman PHYSICS Pierre Agostini, Ferenc Krausz and Anne L’Huillier

MEDICINE: By Staff Reporters

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Dr. Katalin Karikó and Drew Weissman MD PhD just received the Nobel Prize in medicine. Their study of mRNA led to the development of the Covid-19 vaccine.

Oiginally from Hungary, Kariko joined the University of Pennsylvania as a research assistant professor in 1989 to study mRNA. Her grant proposals were constantly rejected, while the rest of the scientific community was slow to catch on to her groundbreaking research. She was never paid more than $60,000 a year. And it was only through a chance encounter at the photocopier that she began to work with Weissman, currently the director of the Penn Institute for RNA Innovation.

The two made the discovery of a lifetime in 2005—that mRNA can be manipulated and injected into the body to activate an immune response. The major academic journals Science and Nature rejected their paper, which received little fanfare even after being published in a less prestigious journal.

So, in 2013, Karikó left Penn for a job at BioNTech where she still works today. And, of course, their breakthrough came in handy during the global pandemic.

Thanks largely to Karikó and Weissman, mRNA vaccine technology, Moderna and BioNTech are working on mRNA vaccines for RSV, HIV, Zika, malaria, shingles, flu, and cancer.

RSV Tests: https://medicalexecutivepost.com/2023/09/25/rsv-vaccine-cdc-oks-pfizer-maternal-shots/

DNA: Testing: https://wordpress.com/post/medicalexecutivepost.com/395273

DANGER: DNA Self-Testing: https://medicalexecutivepost.com/2021/04/25/the-potential-dangers-of-testing-your-own-dna/

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PHYSICS: By Staff Reporters

And, three scientists won the Nobel Prize in physics yesterday for their work on how electrons move around the atom during the tiniest fractions of seconds, a field that could one day lead to better electronics or disease diagnoses.

The award went to Pierre Agostini, Ferenc Krausz and Anne L’Huillier for their study of the tiny part of each atom that races around the center and that is fundamental to virtually everything: chemistry, physics, our bodies and our gadgets.

The movements of electrons inside atoms and molecules are so rapid that they are measured in attoseconds – an almost incomprehensibly short unit of time. “An attosecond is to one second as one second is to the age of the universe,” the committee explained.

“They were able to, in a sense, provide an illumination tool that allows us to watch the assembly of molecules: how things come together to make a molecule,” Bob Rosner, president of the American Physical Society and a professor at the University of Chicago, told CNN.

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NIH: Jeanne Marrazzo MD Succeeds Dr. Anthony Fauci as Infectious Disease Chief

By Staff Reporters

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Jeanne M. Marrazzo MD, a University of Alabama at Birmingham infectious-disease expert, will succeed Anthony S. Fauci this fall as director of the National Institute of Allergy and Infectious Diseases, federal officials announced yesterday.

The $6.3 billion research institute is among the largest of the 27 institutes and centers that constitute the National Institutes of Health, America’s flagship biomedical agency. NIAID is also particularly prominent given its involvement in the response to the coronavirus pandemic and other diseases; it has also received attention because of Dr. Tony Fauci’s own high profile and Republicans’ ongoing efforts to investigate the institute’s workings.

Marrazzo, an infectious-disease physician and epidemiologist who has been a principal investigator on NIH grants since 1997, has focused her research on the human microbiome and the prevention of HIV and infections in the female reproductive tract. She emerged as a frequent commentator during the pandemic, appearing on national television and urging Americans to get vaccinated and take other steps to protect themselves from the virus.

An openly gay physician, Marrazzo has studied barriers to care for LGBTQ patients and advocated to address them.

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PODCAST: A Conversation with Deborah Birx MD

THE COMMON BRIDGE

By Richard Helppie

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20 years ago, as HIV and AIDS threatened vast populations in sub-Saharan Africa, Haiti, Guyana and Vietnam, the US Government made the largest investment in battling a pandemic. Known as the President’s Emergency Plan for AIDS Relief (PEPFAR). May 27th marked the 20th anniversary of the creation of this bipartisan program which coordinated the work of government agencies and local governments to reduce the infections. Dr. Deborah Birx, who had a significant role in the program visits The Common Bridge to talk about PEPFAR’s renewal. Don’t be surprised when the discussion takes a turn to more current events.

In part 2, Dr. Birx responds to Rich’s questions about the decline in scientific credibility.

LINK: https://thecommonbridge.substack.com/p/watch-listen-or-read-information?utm_source=substack&utm_medium=email#play

HERE: https://podcasts.apple.com/us/podcast/richard-helppies-common-bridge/id1485396596

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National HIV Testing Week 2019

National HIV Testing Week 2019

Come to the Mütter Museum for World AIDS Day; December 1st 2019

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I went to medical school in Philadelphia PA, and visited the Mutter Museum many times. If you’ve never been there – I urge you to check it out!

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ESSAY: https://medicalexecutivepost.com/2019/11/19/national-hiv-testing-day/

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Syphilis Is Surging!

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Public Health Officials Aren’t Sure Why?

[By Staff Reporters]

Nationwide, the CDC reports that primary and secondary syphilis rates increased by 10 percent between 2012 and 2013—an infection rate more than twice as high as figures from 2001.

Geography

The Atlanta, Baltimore, Detroit, Los Angles, Miami, Orlando, Portland, San Antonio, San Diego and San Francisco metro areas have some of the highest syphilis rates, according to the CDC.

In the San Francisco Bay area, reported cases rose from 438 in 2009 to 814 in 2013. In Washington, D.C., Dr. Raymond C. Martins, senior director of clinical education at Whitman-Walker Health,says that the clinic saw a 32 percent increase in syphilis cases among patients between 2011 and 2014.

And, in recent months, at least 15 cases of ocular syphilis, a serious complication of the disease that can cause blindness, have been reported in California and Washington state, according to an alert released earlier this month by the CDC.

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PCN

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Assessment

Most of these infections have occurred among HIV-positive men who have sex with men.

Link: http://www.msn.com/en-us/news/us/syphilis-is-surging-and-us-public-health-officials-arent-sure-why/ar-AAb3qBf?ocid=iehp

More:

Even More: Antibiotic Shortages on the Rise in US

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STD Risk Factors to Consider in Public Health

For Men and Women

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There are many factors that affect those at risk for contracting an STD. Many times individuals don’t know or understand which things put them at risk of infection. Some STD’s can be transmitted in surprising ways. For those at risk, regular comprehensive testing can help prevent unintended transmissions. Furthermore, early diagnosis of some STD’s can greatly improve treatment options and avoid hassles associated with full blown infection.

Sensitive Topic

This public service announcement may be a sensitive subject for some ME-P readers. So, the graphic below attempts to use a bit of humor to highlight important things to remember for those who are sexually active.

If you’re concerned about STD’s or want to know more, see please your physician or visit the STD Testing page for additional information.

Assessment

Brought to you by www.HealthTestingCenters.com

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As the Health Care Vote Passes

Another Troubling Insurance Story

By Marian Wang, ProPublica – March 17, 2010 2:03 pm EDT

[picapp align=”none” wrap=”false” link=”term=health+insurance&iid=8337843″ src=”c/e/5/3/President_Obama_signs_baf7.JPG?adImageId=11734822&imageId=8337843″ width=”380″ height=”484″ /]

Reuters filed a stunning report [1] recently about a health insurance company that targeted policyholders with HIV to drop their coverage. It opens with the case of Jerome Mitchell:

Patient Jerome Mitchell

Previously undisclosed records from Mitchell’s case reveal that [health insurance company Fortis [now known as Assurant Health] had a company policy of targeting policyholders with HIV. A computer program and algorithm targeted every policyholder recently diagnosed with HIV for an automatic fraud investigation, as the company searched for any pretext to revoke their policy. As was the case with Mitchell, their insurance policies often were canceled on erroneous information, the flimsiest of evidence, or for no good reason at all, according to the court documents and interviews with state and federal investigators ….

Insurance companies have long engaged in the practice of “rescission,” whereby they investigate policyholders shortly after they’ve been diagnosed with life-threatening illnesses. But, government regulators and investigators who have overseen the actions of Assurant and other health insurance companies say it is unprecedented for a company to single out people with HIV.

The Three Minute Rule

A South Carolina judge who ruled on the case noted that in the meeting in which the rescission committee [2] reviewed Mitchell’s case and decided to cancel his policy, there were more than 40 other customers whose cases were up for review, and “an average of three minutes or less” was spent per customer. Assurant Health told Reuters [1] it doesn’t comment on individual customer claims, while a spokesman added the company disagreed with “certain of the court’s characterizations of Assurant Health’s policies and procedures.” 

Link: http://www.propublica.org/ion/blog/item/as-health-care-vote-nears-another-troubling-insurance-story

Assessment

As the story notes, it’s not just this one insurance company that has been engaging in aggressive rescission. In California, state regulators fined five major health insurance providers—Health Net, Anthem Blue Cross, Blue Shield of California, PacifiCare and Kaiser Permanente—for dropping more than 6,000 sick policyholders. The terms of those settlements, reached in 2008 and 2009 [3], have yet to be implemented in most cases, according to news reports [3] from last week.

Industry Indignation Index: 39

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Understanding Universal Healthcare Precautions

The OSHA Definition for Medicine

By Patricia A. Trites; MPA, CHBC, CHCC, CMP™ (Hon)
Dr. Charles F. Fenton, III; JD, FACFAS
Hope Rachel Hetico; RN, MHA, CMP™

www.HealthcareFinancials.comHO-JFMS-CD-ROM

OSHA defines universal precautions (sometimes referred to as “normal precautions”) as an approach to infection control whereby all human blood and certain human body fluids are treated as if known to be infected by HIV, HBV [hepatitis], or other blood borne pathogens.

 

Assessment

Universal precautions must be observed to prevent contact with blood; or; Other Potentially Infectious Materials [OPIM]. Under circumstances in which differentiation between body fluid types is difficult or impossible, all body fluids should be considered potentially infectious.

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