CRISPR: Play-by-Play of an Experiment

Posted on October 16, 2024 by Dr. David Edward Marcinko MBA MEd CMP™

Scientists in Jennifer Doudna’s lab pull back the veil on their gene-editing process

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Clustered Regularly InterSpaced Palindromic Repeat

By Hayden Field

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CRISPR is a family of DNA sequences found in the genomes of prokaryotic organisms such as bacteria and archaea. These sequences are derived from DNA fragments of bacteriophages that had previously infected the prokaryote. They are used to detect and destroy DNA from similar bacteriophages during subsequent infections

CITE: https://www.amazon.com/Dictionary-Health-Information-Technology-Security/dp/0826149952/ref=sr_1_5?ie=UTF8&s=books&qid=1254413315&sr=1-5

And, we’ve posted about CRISPR before: https://medicalexecutivepost.com/2021/07/08/on-crispr-gene-editing/

So now, what is the use of CRISPR for antiobiotics?

READ: https://www.emergingtechbrew.com/stories/2022/07/26/from-infant-poop-to-trance-music-here-s-a-play-by-play-of-a-crispr-experiment?mid=349b552221c994e2540a304649746d7c

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Thank You

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FINANCIAL PLANNING: https://www.routledge.com/Comprehensive-Financial-Planning-Strategies-for-Doctors-and-Advisors-Best/Marcinko-Hetico/p/book/9781482240283

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On CRISPR Gene Editing

Posted on July 8, 2021 by Dr. David Edward Marcinko MBA MEd CMP™

DEFINITION: CRISPR is a family of DNA sequences found in the genomes of prokaryotic organisms such as bacteria and archaea. These sequences are derived from DNA fragments of bacteriophages that had previously infected the prokaryote. They are used to detect and destroy DNA from similar bacteriophages during subsequent infections

CITE: https://www.amazon.com/Dictionary-Health-Information-Technology-Security/dp/0826149952/ref=sr_1_5?ie=UTF8&s=books&qid=1254413315&sr=1-5

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A Gene Editing Breakthrough
For the first time, CRISPR technology has been used to successfully treat disease in vivo, or inside the human body.

That big medical news was announced Saturday by the biotech startup Intellia Therapeutics and its partner Regeneron, which said their gene-editing techniques reduced the amount of harmful liver protein associated with a genetic nerve disorder. 

What is CRISPR? It stands for “clustered regularly interspaced short palindromic repeats,” and it’s one of those things humans found in nature and then copied.  Bacteria use CRISPR to repel viruses, but humans have harnessed it to ctrl+c, ctrl+v DNA sequences, potentially leading to a revolution in treating disease.  The two scientists who made that breakthrough in 2012, Jennifer Doudna and Emmanuelle Charpentier, won the Nobel Prize in Chemistry last year (Doudna is also a cofounder of Intellia).

Quote du jour: “There’s a feeling like we’re walking through a door here into all kinds of new possibilities. And there’s not many moments in medicine where you get to experience that,” Intellia CEO John Leonard said.  Looking ahead…expect Intellia shares, which have gained 233% since its 2016 IPO, to pop.

CRISPR/Cas9 Genome Editing Technique - Musicians4Freedom

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Nobel Prize in Chemistry 2020

Posted on March 11, 2021 by Dr. David Edward Marcinko MBA MEd CMP™

Nobel Laureate Jennifer Doudna

By Staff Reporters

Even as a child growing up in Hawaii, Nobel Laureate Jennifer Doudna had a strong urge to know things. One day, her father placed the book ‘The Double Helix’ on her bed. This detective-style story about how the structure of the DNA molecule was solved was like nothing she had read in her school textbooks. She was captivated by the scientific process and realised that science is more than just facts.

However, when she started to solve scientific mysteries, her attention was not on DNA, but on its molecular sibling: RNA. This would eventually lead her to the discovery of CRISPR/Cas9 a tool that can be used to change the DNA of organisms with extremely high precision and, in 2020, to the Nobel Prize in Chemistry.

Wishing her a happy birthday today!

Read her story: https://bit.ly/33ID9RQ

MANY THANKS

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